Fluorescent Methods to Study Biological Membranes

Fluorescent Methods to Study Biological Membranes

Author : Yves Mely ,Guy Duportail

Publisher : Springer: 2013 edition

Published date : 2012-10-10

Category : Textbook

*Available in PDF

3 26 486
Chapters Downloads Pages

About the Book

Fluorescent Methods to Study Biological Membranes

Biological membranes play a central role in cell structure, shape and functions. However, investigating the membrane bilayer has proved to be difficult due to its highly dynamic and anisotropic structure, which generates steep gradients at the nanometer scale. Due to the decisive impact of recently developed fluorescence-based techniques, tremendous advances have been made in the last few years in our understanding of membrane characteristics and functions. In this context, the present book illustrates some of these major advances by collecting review articles written by highly respected experts. The book is organized in three parts, the first of which deals with membrane probes and model membranes. The second part describes the use of advanced quantitative and high-resolution techniques to explore the properties of biological membranes, illustrating the key progress made regarding membrane organization, dynamics and interactions. The third part is focused on the investigation of membrane proteins using the same techniques, and notably on the membrane receptors that play a central role in signaling pathways and therapeutic strategies. All chapters provide comprehensive information on membranes and their exploration for beginners in the field and advanced researchers alike.

About the Author

Yves Mely ,Guy Duportail
a few words

Yves Mely ,Guy Duportail

Yves Mély is Professor of biophysics at the University of Strasbourg, since 1998, and Honorary Doctor of the National Taras Shevchenko University of Kiev since 2011. He is a team leader since 1999 and the head of the Laboratory of Biophotonics and Pharmacology, since 2009. He is the Chair of the permanent steering committee of the Methods and Applications in Fluorescence, since 2011. He is member of the CNRS National Committee since 2009 and served from 2003 to 2008 as a co-director of the French network GDR 2588 CNRS ‘Functional microscopy of the living’. His research activities can be divided into two major axes. The first one focuses on the development of innovative environment-sensitive fluorescence probes and fluorescence instrumentation (FLIM, FCS, STORM/PALM, STED, AFM/TIRF). The second axis is related to the characterization in solution and cells of the interaction of HIV-1 proteins with nucleic acids, membranes and host cell proteins. He is particularly interested in the molecular mechanism of the nucleic acid chaperone properties of the HIV-1 nucleocapsid protein and in developing new antiviral strategies targeting this protein. His research activities led to about 200 international publications.

Get the Whole eBook For Free

Not Found? Search here

Similar eBooks


×

CrazyBooks

Login Here

Forgot your account Password ? Click here

Not Registered Yet ? Register here

×

Forgot your account Password ? Click here

Not Registered Yet ? Register here

×

Enter Your Name and Email to Get this eBook